Ranking the Toughest Fights of Floyd Mayweather's Career | News, Scores, Highlights, Stats, and Rumors
Isabella Ramos
Published Mar 25, 2026
More than a decade ago, this fight was the last rematch Floyd Mayweather fought. It's the last time there was any need for him to fight an opponent a second time.
Eight months prior to this, Jose Luis Castillo dropped a unanimous decision to Mayweather that many observers felt he deserved to win. The HBO broadcast team all had the fight for Castillo.
In this rematch, the tough, pressure fighter Castillo once more gave Mayweather almost all he could handle. Once again, it was a very close fight. In this fight, though, I think Mayweather clearly won.